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Metabolic research · RESEARCH PROFILE

SLU-PP-332

A small-molecule tool for studying estrogen-related receptors.

1 specification·11 source documents·Source updated Jun 14, 2026

At a glance

A small-molecule tool for studying estrogen-related receptors.

This profile separates the compound’s scientific background from specification-specific preparation and source schedules. Begin with the research findings and limitations, then select the formulation you want to examine.

How it works

SLU-PP-332 engages estrogen-related receptor signaling associated with energy metabolism. These receptors are distinct from classical estrogen receptors. The compound is not a peptide.[1][11][3]

Potential benefits & side effects

Interpret each outcome in the context of the study population, formulation and evidence type. Research findings do not establish a personal treatment outcome.

Potential benefits & research findings

The source discusses experimental exercise-related metabolic responses. Such findings do not establish that a compound reproduces the broad health effects of exercise in humans.

Read the original publications to see the measured endpoints, comparator, duration and uncertainty. Mechanistic plausibility and a favorable experimental result are different from demonstrated clinical benefit.

Side effects & evidence limitations

Interpret the reported adverse effects together with the study population, route and observation period. Small or short studies can miss uncommon and delayed harms. Evidence from a related compound does not establish the safety of SLU-PP-332.

A comprehensive adverse-effect profile is not established by the source record. Consult the cited studies for what was measured and what remains uncertain.

Sources are available for independent reading. Individual claims and research schedules have not yet undergone an independent clinical review by Pep Science.

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SPECIFICATIONS & SOURCE SCHEDULES

Explore a vial size

Select the exact formulation. Vial content, target dose and prepared concentration are different measurements.

Showing 5 mg · 1 source tables

Source-derived research information. Table phases retain the source’s actual duration; open-ended phases are not converted into a fixed eight-week course. Review the original study before interpreting a schedule.

Murine-Equivalent Protocol (3 mL = ~1.67 mg/mL)

Weeks 1–2Weeks 3–8
PhaseDaily Dose (mcg)Per-Injection Dose (mcg)Units per Injection (mL)
Weeks 1–21250 mcg625 mcg37.5 units (0.375 mL)
Weeks 3–82500 mcg1250 mcg75 units (0.75 mL)

Route & Frequency: Published murine studies used intraperitoneal administration twice daily (25–50 mg/kg)[1][2][3]. Daily mcg values above are expressed for a 25 g mouse. No reputable sources support once-daily subcutaneous use for this compound.

Additional schedule context & duration

Concise summary of the murine-based regimen.

  • Evidence Status: Preclinical only—no human trials exist[1][11].
  • Mechanism: Pan-ERR agonist; activates aerobic-exercise gene program and enhances mitochondrial function.
  • Published Route: Intraperitoneal administration in mice (25–50 mg/kg twice daily).
  • Cycle Length: 8 weeks in published studies.
  • Reconstitution: 3.0 mL per 5 mg vial (~1.67 mg/mL).
  • Storage: Lyophilized frozen; reconstituted refrigerated.

Murine-equivalent dosing framework.

  • Initial Phase (Weeks 1–2): 1250 mcg daily (625 mcg per injection, twice daily).
  • Maintenance Phase (Weeks 3–8): 2500 mcg daily (1250 mcg per injection, twice daily).
  • Frequency: Twice per day, reflecting published murine regimens[1][2][3].
  • Route: Intraperitoneal (as studied in preclinical models).
  • Timing: Consistent intervals between administrations.

Read this source protocol ↗ · View cited documents ↓

Preparation

Preparation and stability depend on the formulation, diluent, container and handling. The source-specific notes below apply to the selected record.
Reconstitution Steps
  1. Draw 3.0 mL bacteriostatic water with a sterile syringe.
  2. Inject slowly down the vial wall; avoid foaming.
  3. Gently swirl/roll until dissolved (do not shake).
  4. Label and refrigerate at 2–8 °C (35.6–46.4 °F), protected from light.

Critical: This guide reflects preclinical murine research only. This information is for educational and research purposes exclusively—not for human consumption. No human safety or efficacy data exist for SLU-PP-332.

Storage Instructions

Proper storage preserves compound stability[7][8][9][10].

  • Lyophilized: Store at −20 °C (−4 °F) in dry, dark conditions; minimize moisture exposure.
  • Reconstituted: Refrigerate at 2–8 °C (35.6–46.4 °F); avoid freeze–thaw cycles.
  • Allow vials to reach room temperature before opening to reduce condensation.
  • Protect from light during storage and handling.

Materials & quantity planning

Source materials checklist · 5 mg

Based on an 8–16 week murine-equivalent protocol with twice-daily administration.

  • Peptide Vials (SLU-PP-332, 5 mg each):

    • 8 weeks ≈ 25 vials
    • 12 weeks ≈ 39 vials
    • 16 weeks ≈ 53 vials
  • Insulin Syringes (U-100):

    • Per week: 14 syringes (2/day)
    • 8 weeks: 112 syringes
    • 12 weeks: 168 syringes
    • 16 weeks: 224 syringes
  • Bacteriostatic Water (10 mL bottles): Use ~3.0 mL per vial for reconstitution.

    • 8 weeks (25 vials): 75 mL8 × 10 mL bottles
    • 12 weeks (39 vials): 117 mL12 × 10 mL bottles
    • 16 weeks (53 vials): 159 mL16 × 10 mL bottles
  • Alcohol Swabs: One for the vial stopper + one for the injection site each administration.

    • Per week: 28 swabs (4/day)
    • 8 weeks: 224 swabs → recommend 3 × 100-count boxes
    • 12 weeks: 336 swabs → recommend 4 × 100-count boxes
    • 16 weeks: 448 swabs → recommend 5 × 100-count boxes


Calculate a phased quantity

Enter each finite phase from the schedule you are studying. Open-ended phases need an explicit duration. Calculation uses 5 mg per vial and 3 mL per vial.

Complete each phase to calculate totals.

Quantity estimates exclude preparation losses and expiry. Follow the formulation’s handling and disposal requirements.

FOLLOW THE EVIDENCE

References & further reading

Original publications and source documents cited across this product’s variants. A listed source is not an independent endorsement of a dosing schedule.

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